The white-tailed antelope squirrel, Ammospermophilus leucurus, occurs in much of the western United States, as well as in Mexico. The species is common in Utah, where it can be found throughout most of the state in desert and shrubland areas with sparse vegetation. White-tailed antelope squirrels are active year-round, and are most active during the day. Nights and other periods of inactivity are spent in underground burrows. Individuals are often solitary.

Females may give birth to one or two litters of five to fourteen young during the spring of each year. The white-tailed antelope squirrel is a generalist feeder, eating such items as seeds, other plant material, small vertebrates, insects, and carrion (animals already dead). Food may be stored when it is plentiful.